San Francisco 49ers wide receiver Deebo Samuel (ribs) is not practicing on Wednesday.

Tennessee Titans wide receiver Treylon Burks (concussion) is questionable for Week 16 against the Houston Texans on Saturday.

Tennessee Titans quarterback Ryan Tannehill (ankle) is out for Week 16 against the Houston Texans on Saturday.

Tennessee Titans quarterback Ryan Tannehill (ankle) has an "uphill battle" to play Week 16 against the Houston Texans, reports Tom Pelissero of NFL Network.

Christian McCaffrey is the obvious top MVP play, but should you dodge the chalk and use someone else in the multiplier spot on this single-game slate?

Austin Ekeler came back to a massive role in Week 12, and it makes him a top priority for Week 13's NFL DFS slate. Which other situations should influence our roster decisions on Sunday?

The Bucs and Packers square off in a potential shootout on Sunday, putting a number of their offensive weapons on the Week 6 fantasy radar.

Russell Wilson and the Seahawks get a dream matchup against the fast-paced Cardinals. Which other game scripts look fantasy friendly in Week 16?

What should you know about every main-slate game in Week 16?

With just one more week of season-long fantasy football, who should you be adding to help bring home a championship?